Protein Microarray Characterization of the S-Nitrosoproteome
نویسندگان
چکیده
منابع مشابه
Protein Microarray Characterization of the S-Nitrosoproteome*□S
Nitric oxide (NO) mediates a substantial part of its physiologic functions via S-nitrosylation, however the cellular substrates for NO-mediated S-nitrosylation are largely unknown. Here we describe the S-nitrosoproteome using a high-density protein microarray chip containing 16,368 unique human proteins. We identified 834 potentially Snitrosylated human proteins. Using a unique and highly speci...
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A protein microarray-based analysis of S-nitrosylation.
The ubiquitous cellular influence of nitric oxide (NO) is exerted substantially through protein S-nitrosylation. Whereas NO is highly promiscuous, physiological S-nitrosylation is typically restricted to one or very few Cys residue(s) in target proteins. The molecular basis for this specificity may derive from properties of the target protein, the S-nitrosylating species, or both. Here, we desc...
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ژورنال
عنوان ژورنال: Molecular & Cellular Proteomics
سال: 2014
ISSN: 1535-9476
DOI: 10.1074/mcp.m113.032235